Coronary Graft Failure

Coronary artery bypass surgery has been developed since 1960s to overcome proximal coronary artery disease. Worldwide, the number of patients that are undergoing coronary artery bypass surgery is steadily increasing. Depending on diverse risk factors, one fifth of grafts are occluded at 1 year. For the remaining, graft patency last usually 8-15 years. This book brings together the main specialists in the field to review the current evidence on epidemiology, pathophysiology, diagnostic, new imaging techniques and specific therapeutic modalities. This volume aims to update a complex subject represented by coronary graft failure. The authors of this monograph are interventional cardiologists, cardiovascular surgeons and research scientists, who will be creating four parts and 71 chapters that are divided in order to give a uniform interpretation of this condition including all aspects of coronary graft failure This book not only provides the most up-to-dated scientific evidence in the field but in a two-step manner. Each chapter is divided into a at a glance part that reflects the basic evidence on the topic, and a "full picture" part that brings all what the advanced reader should be brought with.

This book evaluates the current state of knowledge regarding coronary graft failure. It reviews how graft failure can be caused by many factors including the complexity of multiple coronary vessel lesions with surgical revascularization, numerous pathogenic mechanisms of arterial or venous graft dysfunction in the presence of other comorbidities (diabetes mellitus, hypertension and dyslipidemia), and the development of intra-graft atherosclerosis process or distally to the graft. Coronary Graft Failure represents the accumulation of data on pathophysiological mechanisms of maintenance and progression of this pathology, while quantifying of diagnostic methods and the value of each in part for the best approach strategy for planning of recurrent revascularization (redo). It also evaluates the therapeutic solutions available for graft revascularization. As such, it will be a vital reference for all involved in the management of patients undergoing graft restenosis whether interventional or surgical.